Wednesday, April 27, 2016

Genomics FOTD

The average human has a genome that differs from the human reference genome at about 3-4 million sites (out of 3.2 billion).

Asian, European, and (Native) American population groups (out of 26 population groups total; 10 Asian, 5 Eur, 6 NA, 5 African) went through extreme population bottlenecks 15-20,000 years ago where the effective population sizes of each were reduced to less than 1,500 individuals. The simultaneous African bottlenecks was a good deal less severe with effective population sizes > 4,500. Most rebounded with extreme population growth shortly thereafter.